Publications

343 entries « 7 of 7 »

2009

Durham, Elizabeth; Dorr, Brent; Woetzel, Nils; Staritzbichler, René; Meiler, Jens

Solvent accessible surface area approximations for rapid and accurate protein structure prediction Journal Article

In: J Mol Model, vol. 15, no. 9, pp. 1093–1108, 2009, ISSN: 0948-5023.

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Koehler, Julia; Woetzel, Nils; Staritzbichler, René; Sanders, Charles R; Meiler, Jens

A unified hydrophobicity scale for multispan membrane proteins Journal Article

In: Proteins, vol. 76, no. 1, pp. 13–29, 2009, ISSN: 1097-0134.

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Lindert, Steffen; Staritzbichler, René; Wötzel, Nils; Karakaş, Mert; Stewart, Phoebe L; Meiler, Jens

EM-fold: De novo folding of alpha-helical proteins guided by intermediate-resolution electron microscopy density maps Journal Article

In: Structure, vol. 17, no. 7, pp. 990–1003, 2009, ISSN: 1878-4186.

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Stepanovic, Svetlana Z; Potet, Franck; Petersen, Christina I; Smith, Jarrod A; Meiler, Jens; Balser, Jeffrey R; Kupershmidt, Sabina

The evolutionarily conserved residue A653 plays a key role in HERG channel closing Journal Article

In: J Physiol, vol. 587, no. Pt 11, pp. 2555–2566, 2009, ISSN: 1469-7793.

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Friedland, Gregory D; Lakomek, Nils-Alexander; Griesinger, Christian; Meiler, Jens; Kortemme, Tanja

A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family Journal Article

In: PLoS Comput Biol, vol. 5, no. 5, pp. e1000393, 2009, ISSN: 1553-7358.

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Lindert, Steffen; Stewart, Phoebe L; Meiler, Jens

Hybrid approaches: applying computational methods in cryo-electron microscopy Journal Article

In: Curr Opin Struct Biol, vol. 19, no. 2, pp. 218–225, 2009, ISSN: 1879-033X.

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Kaufmann, Kristian W; Dawson, Eric S; Henry, L Keith; Field, Julie R; Blakely, Randy D; Meiler, Jens

Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies Journal Article

In: Proteins, vol. 74, no. 3, pp. 630–642, 2009, ISSN: 1097-0134.

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Fallen, Katherine; Banerjee, Sreedatta; Sheehan, Jonathan; Addison, Daniel; Lewis, L Michelle; Meiler, Jens; Denton, Jerod S

The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating Journal Article

In: Channels (Austin), vol. 3, no. 1, pp. 57–68, 2009, ISSN: 1933-6969.

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Koehler, Julia; Mueller, Ralf; Meiler, Jens

Improved prediction of trans-membrane spans in proteins using an Artificial Neural Network Journal Article

In: IEEE Symp Comput Intell Bioinforma Comput Biol Proc, vol. 2009, pp. 68–74, 2009.

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2008

Lakomek, Nils-Alexander; Lange, Oliver F; Walter, Korvin F A; Farès, Christophe; Egger, Dalia; Lunkenheimer, Peter; Meiler, Jens; Grubmüller, Helmut; Becker, Stefan; de Groot, Bert L; Griesinger, Christian

Residual dipolar couplings as a tool to study molecular recognition of ubiquitin Journal Article

In: Biochem Soc Trans, vol. 36, no. Pt 6, pp. 1433–1437, 2008, ISSN: 1470-8752.

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Dong, Elizabeth; Smith, Jarrod; Heinze, Sten; Alexander, Nathan; Meiler, Jens

BCL::Align-sequence alignment and fold recognition with a custom scoring function online Journal Article

In: Gene, vol. 422, no. 1-2, pp. 41–46, 2008, ISSN: 0378-1119.

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Kang, Congbao; Tian, Changlin; Sönnichsen, Frank D; Smith, Jarrod A; Meiler, Jens; George, Alfred L; Vanoye, Carlos G; Kim, Hak Jun; Sanders, Charles R

Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel Journal Article

In: Biochemistry, vol. 47, no. 31, pp. 7999–8006, 2008, ISSN: 1520-4995.

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Lakomek, Nils-Alexander; Walter, Korvin F A; Farès, Christophe; Lange, Oliver F; de Groot, Bert L; Grubmüller, Helmut; Brüschweiler, Rafael; Munk, Axel; Becker, Stefan; Meiler, Jens; Griesinger, Christian

Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics Journal Article

In: J Biomol NMR, vol. 41, no. 3, pp. 139–155, 2008, ISSN: 0925-2738.

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Hanson, Susan M; Dawson, Eric S; Francis, Derek J; Eps, Ned Van; Klug, Candice S; Hubbell, Wayne L; Meiler, Jens; Gurevich, Vsevolod V

A model for the solution structure of the rod arrestin tetramer Journal Article

In: Structure, vol. 16, no. 6, pp. 924–934, 2008, ISSN: 0969-2126.

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Lange, Oliver F; Lakomek, Nils-Alexander; Farès, Christophe; Schröder, Gunnar F; Walter, Korvin F A; Becker, Stefan; Meiler, Jens; Grubmüller, Helmut; Griesinger, Christian; de Groot, Bert L

Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution Journal Article

In: Science, vol. 320, no. 5882, pp. 1471–1475, 2008, ISSN: 1095-9203.

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Alexander, Nathan; Bortolus, Marco; Al-Mestarihi, Ahmad; Mchaourab, Hassane; Meiler, Jens

De novo high-resolution protein structure determination from sparse spin-labeling EPR data Journal Article

In: Structure, vol. 16, no. 2, pp. 181–195, 2008, ISSN: 0969-2126.

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2007

Smith, Jarrod A; Vanoye, Carlos G; George, Alfred L; Meiler, Jens; Sanders, Charles R

Structural models for the KCNQ1 voltage-gated potassium channel Journal Article

In: Biochemistry, vol. 46, no. 49, pp. 14141–14152, 2007, ISSN: 0006-2960.

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Henry, L Keith; Meiler, Jens; Blakely, Randy D

Bound to be different: neurotransmitter transporters meet their bacterial cousins Journal Article

In: Mol Interv, vol. 7, no. 6, pp. 306–309, 2007, ISSN: 1534-0384.

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McKinney, Brett A; Kallewaard, Nicole L; Crowe, James E; Meiler, Jens

Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site Journal Article

In: Immunome Res, vol. 3, pp. 8, 2007, ISSN: 1745-7580.

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Reese, Marcel; Sánchez-Pedregal, Víctor M; Kubicek, Karel; Meiler, Jens; Blommers, Marcel J J; Griesinger, Christian; Carlomagno, Teresa

Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution Journal Article

In: Angew Chem Int Ed Engl, vol. 46, no. 11, pp. 1864–1868, 2007, ISSN: 1433-7851.

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2006

Zanghellini, Alexandre; Jiang, Lin; Wollacott, Andrew M; Cheng, Gong; Meiler, Jens; Althoff, Eric A; Röthlisberger, Daniela; Baker, David

New algorithms and an in silico benchmark for computational enzyme design Journal Article

In: Protein Sci, vol. 15, no. 12, pp. 2785–2794, 2006, ISSN: 0961-8368.

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Meiler, Jens; Baker, David

ROSETTALIGAND: protein-small molecule docking with full side-chain flexibility Journal Article

In: Proteins, vol. 65, no. 3, pp. 538–548, 2006, ISSN: 1097-0134.

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Sánchez-Pedregal, Víctor M; Kubicek, Karel; Meiler, Jens; Lyothier, Isabelle; Paterson, Ian; Carlomagno, Teresa

The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide Journal Article

In: Angew Chem Int Ed Engl, vol. 45, no. 44, pp. 7388–7394, 2006, ISSN: 1433-7851.

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Lakomek, Nils A; Carlomagno, Teresa; Becker, Stefan; Griesinger, Christian; Meiler, Jens

A thorough dynamic interpretation of residual dipolar couplings in ubiquitin Journal Article

In: J Biomol NMR, vol. 34, no. 2, pp. 101–115, 2006, ISSN: 0925-2738.

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2005

Lakomek, Nils A; Farès, Christophe; Becker, Stefan; Carlomagno, Teresa; Meiler, Jens; Griesinger, Christian

Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin Journal Article

In: Angew Chem Int Ed Engl, vol. 44, no. 47, pp. 7776–7778, 2005, ISSN: 1433-7851.

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Sánchez-Pedregal, Víctor M; Reese, Marcel; Meiler, Jens; Blommers, Marcel J J; Griesinger, Christian; Carlomagno, Teresa

The INPHARMA method: protein-mediated interligand NOEs for pharmacophore mapping Journal Article

In: Angew Chem Int Ed Engl, vol. 44, no. 27, pp. 4172–4175, 2005, ISSN: 1433-7851.

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Meiler, Jens; Baker, David

The fumarate sensor DcuS: progress in rapid protein fold elucidation by combining protein structure prediction methods with NMR spectroscopy Journal Article

In: J Magn Reson, vol. 173, no. 2, pp. 310–316, 2005, ISSN: 1090-7807.

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Bradley, Philip; Malmström, Lars; Qian, Bin; Schonbrun, Jack; Chivian, Dylan; Kim, David E; Meiler, Jens; Misura, Kira M S; Baker, David

Free modeling with Rosetta in CASP6 Journal Article

In: Proteins, vol. 61 Suppl 7, pp. 128–134, 2005, ISSN: 1097-0134.

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Graña, Osvaldo; Baker, David; MacCallum, Robert M; Meiler, Jens; Punta, Marco; Rost, Burkhard; Tress, Michael L; Valencia, Alfonso

CASP6 assessment of contact prediction Journal Article

In: Proteins, vol. 61 Suppl 7, pp. 214–224, 2005, ISSN: 1097-0134.

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2004

Meiler, Jens; Köck, Matthias

Novel methods of automated structure elucidation based on 13C NMR spectroscopy Journal Article

In: Magn Reson Chem, vol. 42, no. 12, pp. 1042–1045, 2004, ISSN: 0749-1581.

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Kuhn, Michael; Meiler, Jens; Baker, David

Strand-loop-strand motifs: prediction of hairpins and diverging turns in proteins Journal Article

In: Proteins, vol. 54, no. 2, pp. 282–288, 2004, ISSN: 1097-0134.

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Griesinger, Christian; Peti, Wolfgang; Meiler, Jens; Brüschweiler, Rafael

Projection angle restraints for studying structure and dynamics of biomolecules Journal Article

In: Methods Mol Biol, vol. 278, pp. 107–121, 2004, ISSN: 1064-3745.

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2003

Meiler, Jens; Baker, David

Rapid protein fold determination using unassigned NMR data Journal Article

In: Proc Natl Acad Sci U S A, vol. 100, no. 26, pp. 15404–15409, 2003, ISSN: 0027-8424.

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Meiler, Jens; Baker, David

Coupled prediction of protein secondary and tertiary structure Journal Article

In: Proc Natl Acad Sci U S A, vol. 100, no. 21, pp. 12105–12110, 2003, ISSN: 0027-8424.

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Meiler, Jens; Peti, Wolfgang; Griesinger, Christian

Dipolar couplings in multiple alignments suggest alpha helical motion in ubiquitin Journal Article

In: J Am Chem Soc, vol. 125, no. 27, pp. 8072–8073, 2003, ISSN: 0002-7863.

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Carlomagno, Teresa; Blommers, Marcel J J; Meiler, Jens; Jahnke, Wolfgang; Schupp, Thomas; Petersen, Frank; Schinzer, Dieter; Altmann, Karl-Heinz; Griesinger, Christian

The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents Journal Article

In: Angew Chem Int Ed Engl, vol. 42, no. 22, pp. 2511–2515, 2003, ISSN: 1433-7851.

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Meiler, Jens

PROSHIFT: protein chemical shift prediction using artificial neural networks Journal Article

In: J Biomol NMR, vol. 26, no. 1, pp. 25–37, 2003, ISSN: 0925-2738.

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Bradley, Philip; Chivian, Dylan; Meiler, Jens; Misura, Kira M S; Rohl, Carol A; Schief, William R; Wedemeyer, William J; Schueler-Furman, Ora; Murphy, Paul; Schonbrun, Jack; Strauss, Charles E M; Baker, David

Rosetta predictions in CASP5: successes, failures, and prospects for complete automation Journal Article

In: Proteins, vol. 53 Suppl 6, pp. 457–468, 2003, ISSN: 1097-0134.

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2002

Hutter, Michael C; Krebs, Joachim; Meiler, Jens; Griesinger, Christian; Carafoli, Ernesto; Helms, Volkhard

A structural model of the complex formed by phospholamban and the calcium pump of sarcoplasmic reticulum obtained by molecular mechanics Journal Article

In: Chembiochem, vol. 3, no. 12, pp. 1200–1208, 2002, ISSN: 1439-4227.

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Meiler, Jens; Maier, Walter; Will, Martin; Meusinger, Reinhard

Using neural networks for (13)c NMR chemical shift prediction-comparison with traditional methods Journal Article

In: J Magn Reson, vol. 157, no. 2, pp. 242–252, 2002, ISSN: 1090-7807.

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Peti, Wolfgang; Meiler, Jens; Brüschweiler, Rafael; Griesinger, Christian

Model-free analysis of protein backbone motion from residual dipolar couplings Journal Article

In: J Am Chem Soc, vol. 124, no. 20, pp. 5822–5833, 2002, ISSN: 0002-7863.

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Meiler, Jens; Will, Martin

Genius: a genetic algorithm for automated structure elucidation from 13C NMR spectra Journal Article

In: J Am Chem Soc, vol. 124, no. 9, pp. 1868–1870, 2002, ISSN: 0002-7863.

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Meiler, Jens; Sanli, Erdogan; Junker, Jochen; Meusinger, Reinhard; Lindel, Thomas; Will, Martin; Maier, Walter; Köck, Matthias

Validation of structural proposals by substructure analysis and 13C NMR chemical shift prediction Journal Article

In: J Chem Inf Comput Sci, vol. 42, no. 2, pp. 241–248, 2002, ISSN: 0095-2338.

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343 entries « 7 of 7 »