About The Meiler Lab
The Meiler Lab is uniquely located both in the United States and Germany, and is actively involved in developing the Rosetta computational modeling software suite together with 15 other laboratories in the United States. As an integral part of the Rosetta community, the Meiler lab works to better understand macromolecular interactions, design custom molecules, and develop efficient ways to search conformational and sequence space.
1
To enable protein structure elucidation of membrane proteins the primary target of most therapeutics and large macromolecular complexes such as viruses.
2
Design proteins with novel structure and/or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.
3
Understand the relation between chemical structure and biological activity quantitatively in order to design more efficient and more specific drugs.
Recent News

Congratulations to Eli on winning the 2024 Karpay Award in Structural Biology! He has worked in the Jens Meiler...
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Karen Pu, class of 2024 at Vanderbilt, was featured for her excellent research in the Meiler lab through the...
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The Meiler lab hosted a four-day developer retreat in the Great Smoky Mountains from July 24-27th. The focus of...
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Meiler lab graduate student, Hope Woods, successfully defended her thesis “Development of Frameworks for Computational Protein Structure Prediction Applications...
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Congratulations to Ben Brown, research assistant professor in the Meiler lab, on his recent NIH DP1 award for his...
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