About The Meiler Lab
The Meiler Lab is uniquely located both in the United States and Germany, and is actively involved in developing the Rosetta computational modeling software suite together with 15 other laboratories in the United States. As an integral part of the Rosetta community, the Meiler lab works to better understand macromolecular interactions, design custom molecules, and develop efficient ways to search conformational and sequence space.
1
To enable protein structure elucidation of membrane proteins the primary target of most therapeutics and large macromolecular complexes such as viruses.
2
Design proteins with novel structure and/or function to explore novel approaches to protein therapeutics and deepen our understanding of protein folding pathways.
3
Understand the relation between chemical structure and biological activity quantitatively in order to design more efficient and more specific drugs.
Recent News
After her recent successful honors defense, Alex Eisenreich, Meiler lab undergraduate researcher, was further recognized at the annual Chemistry...
Continue reading...Eli McDonald passed the defense of his graduate research thesis “Structural and Proteostatic Mechanisms of Cystic Fibrosis Corrector Response.”...
Continue reading...Alex Eisenreich, an undergraduate in the chemistry department and Meiler lab researcher, successfully defended her honors thesis in March....
Continue reading...Congratulations to Eli on winning the 2024 Karpay Award in Structural Biology! He has worked in the Jens Meiler...
Continue reading...Karen Pu, class of 2024 at Vanderbilt, was featured for her excellent research in the Meiler lab through the...
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