Rosetta Workshop 2018

Below are the updated tutorials from the Rosetta Workshop held in November 2018 at Vanderbilt Univers

These tutorials have been updated to work with the recent REF2015 energy function, and are based on the Rosetta 2018.42.60459 weekly release. They should also mostly work with the Rosetta 3.10 release, though the 3.10 release has a bug in the InterfaceAnalyzer mover used in some of the tutorials.

These tutorials were covered during a 3-day hands-on workshop which included PowerPoint presentations and step-by-step instructions for worked examples.

Tutorial 1: Ab initio Folding

• Materials (zip)

Tutorial 2: RosettaCM multi-template comparative modeling

• Materials (zip)

Tutorial 3: Protein-Protein Docking

• Materials (zip)

Tutorial 4: Protein-small molecule docking

• Materials (zip)

Tutorial 5: Single and Multi-state protein design

• Materials (zip)

Tutorial 6: Scaffolding and sidechain/backbone (epitope) grafting

• Materials (zip)

Short Talks: Input and Output, Navigating Rosetta, Rosetta Energy Function, RosettaScripts, Using experimental data

• Materials (zip)