The new 3PB strorage module on Vanderbilt's compute cluster has exhibited extremely slow response. This is being addressed by IT teams - and we expect improvements within the week. Our web server will be returned to service at that point.
Although storage performance is problematic, limited runs of VUStruct remain available at Vanderbilt - outside the web input form.
Please Contact Us if you would like to open a collaboration.
Post-translational modifications to proteins are often critical to function. However, these modifications (phosphorylation, glycosylation, and others) are typically unresolved in experimental X-ray structures, and never seen in model structures. Sequence-based prediction of post-translational modification sites has been evolving in recent decades, and we have integrated MutsiteDeep (Wang et al. 2017), the first deep-learning framework for prediction of these sites.
We report variants at sites predicted to have at least a 50% likelihood of post-translational modification.