On February 17 (last week), Vanderbilt's ACCRE cluster was to have been upgraded with 3PB of new storage. This critical upgrade is not in production, although we expect resolution within a very few days. Our web server will be returned to service at that point.
Although storage is temporarily constrained, limited runs of VUStruct remain available at Vanderbilt - outside the web input form.
Please Contact Us if you would like to open a collaboration.
We shall update this page at least weekly.Post-translational modifications to proteins are often critical to function. However, these modifications (phosphorylation, glycosylation, and others) are typically unresolved in experimental X-ray structures, and never seen in model structures. Sequence-based prediction of post-translational modification sites has been evolving in recent decades, and we have integrated MutsiteDeep (Wang et al. 2017), the first deep-learning framework for prediction of these sites.
We report variants at sites predicted to have at least a 50% likelihood of post-translational modification.