Rosetta Workshop 2023

A workshop for general Rosetta protocols was held December 4th to December 6th, 2023. The tutorials for the workshop consisted of both introductory presentations as well as work-at-your-own-pace exercises.

The workshop materials are written for Rosetta version 2023.45

You may also be interested in the Youtube playlist of recorded presentations from the 2020 virtual workshop, which had some similar tutorials.

*If you experience difficulties downloading the following content, please try again on a different or updated browser.

Introductory Presentations:

• Introduction by Jens Meiler (pdf)
• Rosetta IO & Overview (pdf)
• RosettaScripts (pdf)
• Rosetta Energy Function (pdf)

Main Tutorials:

Tutorial 1: Machine Learning Structure Prediction (RoseTTAFold and AlphaFold)

• Presentation (pdf)
• Tutorial (pdf)
• Materials (zip)

Tutorial 2: Machine Learning in Rosetta

• Presentation (pdf)
• Tutorial (pdf)
• Materials (zip)

Tutorial 3: Protein-Protein Docking

• Presentation (pdf)
• Tutorial (pdf)
• Materials (zip)

Tutorial 4: Small Molecule Ligand Docking

• Presentation (pdf)
• Tutorial (pdf)
• Materials (zip)

Tutorial 5: RFDiffusion

• Presentation (pdf)
• Tutorial (pdf)
• Materials (zip)

Tutorial 6: Macrocyclic peptide design with Noncanonical Amino Acids

• Presentation (pdf)
• Tutorial (pdf)
• Materials (zip)